Visualising Cancer In 3D: 3-Dimensional Tissue Imaging for Management Of Cutaneous Basal Cell Carcinoma
Applied/Translational Research
Singapore Health Biomedical Congress
National Healthcare Group
31 December 2022
To develop a method to examine cancer margins in 3D. 3D tissue imaging is a powerful tool for assessing cancer margins, improving outcomes through better surgical precision.
Year Submitted: 2022
Published Date: 31 December 2022
Tags: Applied/Translational Research, Qualitative Research
About this Content
Aims
To develop a method to examine cancer margins in 3D.
Background
Traditional methods for examining cancer margins are limited. 3D imaging offers a comprehensive approach to assessing unexcised tumour tissue.
Methods
3D tissue imaging was used to evaluate cancer margins with fluorescence microscopy to detect tumour, nerve, and blood vessel involvement.
Results
3D imaging successfully visualized cancer margins, providing better sampling of unexcised tumours and detecting critical anatomical features like nerve and blood vessel involvement.
Conclusion
3D tissue imaging is a powerful tool for assessing cancer margins, improving outcomes through better surgical precision.
Lessons Learnt
Method optimization was necessary to integrate 3D imaging into clinical workflows. Adjustments ensured accuracy in human sample variability.
Additional Information
SHBC 2022 Basic Science/Translational Research Poster Category (Gold Award)
Keywords
Cancer Margin Management, 3D Imaging, Whole-Tissue Imaging, Basal Cell Carcinoma
Innovators' Details
Innovators' Details
Healthcare Cluster(s) | National Healthcare Group |
Organization(s) Involved | National Skin Centre, Agency for Science Technology and Research, Lee Kong Chian School of Medicine NTU Singapore, Yong Loo Lin School of Medicine |
Platform(s) | Singapore Health Biomedical Congress |
Healthcare Professional Group(s) | Ancillary Care |
Applicable Specialty or Discipline | Clinical Research, Oncology, Dermatology |
Project Lead(s) | Tey Hong Liang |
Project Member(s) | Yingrou Tan |
Connect with this contributor!
Dr Tan Yingrou - ytan@nsc.com.sg