[AVBC 2025] Nurse-led Optimization of Volume and blood pressure - Enabling at multi-Levels using TechnologY
Care Continuum
Care Process & Redesign
Appropriate & Value-based Care Conference
SingHealth
28 November 2025
To explore the intricate relationships between health-related quality of life (HRQoL) and multifaceted patient. This analysis highlights the interplay between sociodemographic factors, clinical parameters, and patient-reported outcomes in CKD.
Year Submitted: 2025
Published Date: 28 November 2025
Tags: Care Process ＆ Redesign, Care Continuum, Value Based Care, Patient Reported Outcome Measures, Chronic Care, Self Care
About this Content
Aims
To explore the intricate relationships between health-related quality of life (HRQoL) and multifaceted patient characteristics within a Nurse-led Optimization of Volume and blood pressure - Enabling at multi-Levels using TechnologY (NOVELTY) clinic, specifically examining the interplay between clinical parameters and patient-reported outcomes in CKD patients with fluid overload.
Background
The pervasive nature of fluid overload in chronic kidney disease (CKD) profoundly influences patients' perceived well-being and daily functioning. While clinical parameters traditionally guide management, patient-reported outcome measures (PROMs) offer invaluable insights into the lived experience of individuals grappling with this challenging condition.
Methods
The cohort comprised 65 participants (56.9% male), predominantly of Chinese ethnicity (72.3%), with a median age of 67.4 years. Analysis revealed compelling associations between diminished quality of life (manifested as elevated EQ5D5L scores) and several key determinants: advanced age, female gender, unemployment, modest monthly income ($2,000), heightened sarcopenia risk, substantial comorbidity burden, and two or more fluid overload-related symptoms in the past 6 months. Notably, deteriorating renal function demonstrated a correlation with compromised quality of life metrics.
Results
The cohort comprised 65 participants (56.9% male), predominantly of Chinese ethnicity (72.3%), with a median age of 67.4 years. Analysis revealed compelling associations between diminished quality of life (manifested as elevated EQ5D5L scores) and several key determinants: advanced age, female gender, unemployment, modest monthly income ($2,000), heightened sarcopenia risk, substantial comorbidity burden, and two or more fluid overload-related symptoms in the past 6 months. Notably, deteriorating renal function demonstrated a correlation with compromised quality of life metrics.
Conclusion
This analysis highlights the interplay between sociodemographic factors, clinical parameters, and patient-reported outcomes in CKD patients with fluid overload. These findings advocate for the systematic integration of PROMs in nurse-led clinics, facilitating targeted interventions for vulnerable subgroups and potentially enhancing the trajectory of patient care.
Lessons Learnt
The study highlights the importance of integrating patient-reported outcome measures in clinical settings to better understand and address the multifaceted needs of CKD patients with fluid overload.
Keywords
CKD, fluid overload, PROMs, quality of life, nephrology
Innovators' Details
Innovators' Details
Healthcare Cluster(s) | SingHealth |
Organization(s) Involved | Singapore General Hospital |
Platform(s) | Appropriate & Value-based Care Conference |
Healthcare Professional Group(s) | Nursing |
Applicable Specialty or Discipline | Nephrology |
Project Lead(s) | Cynthia Lim Ciwei |
Project Member(s) | Li Choo Ng |
Connect with this contributor!
Cynthia Lim Ciwei - cynthia.lim.c.w@singhealth.com.sg