Association of Nitrogen Balance with Skeletal Muscle Mass in Singapore’s T2D Population
Applied/Translational Research
Singapore Health Biomedical Congress
National Healthcare Group
31 December 2022
To measure urinary urea nitrogen (UUN) and examine the correlation of nitrogen balance (NBAL) with skeletal muscle mass and. NBAL is a promising indicator for monitoring skeletal muscle health in T2D populations, though longitudinal studies are needed for.
Year Submitted: 2022
Published Date: 31 December 2022
Tags: Applied/Translational Research, Quantitative Research
About this Content
Aims
To measure urinary urea nitrogen (UUN) and examine the correlation of nitrogen balance (NBAL) with skeletal muscle mass and frailty parameters.
Background
Poorly controlled diabetes accelerates muscle catabolism; nitrogen balance offers an objective measure of protein intake adequacy, essential for preserving muscle mass.
Methods
Cross-sectional study of 161 T2D participants. Data collected included UUN, skeletal muscle mass, and frailty parameters through standardized methods.
Results
Positive correlations were found between NBAL and skeletal muscle mass, phase angle, and hand grip strength. Higher NBAL tertiles associated with better muscle metrics.
Conclusion
NBAL is a promising indicator for monitoring skeletal muscle health in T2D populations, though longitudinal studies are needed for further validation.
Lessons Learnt
NBAL offers an objective measure to assess nutritional status and guide precise protein prescriptions to prevent frailty/malnutrition.
Keywords
NBAL (Nitrogen Balance), Malnutrition Risk Detection
Innovators' Details
Innovators' Details
Healthcare Cluster(s) | National Healthcare Group |
Organization(s) Involved | Yishun Health |
Platform(s) | Singapore Health Biomedical Congress |
Healthcare Professional Group(s) | Allied Health |
Applicable Specialty or Discipline | Nutrition ＆ Dietetics, Geriatric Medicine, Orthopaedics |
Project Lead(s) | Kwan Tsz Kiu |
Project Member(s) | Lim Su Chi |
Connect with this contributor!
Kwan Tsz Kiu - kwan.tsz.kiu@ktph.com.sg